概述

  • 产品名称
    Anti-NETO2抗体[EPR3497]
    参阅全部 NETO2 一抗
  • 描述
    兔单克隆抗体[EPR3497] to NETO2
  • 经测试应用
    适用于: WB, IPmore details
    不适用于: Flow Cyt,ICC or IHC-P
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in human NETO2

  • 阳性对照
    • Human cerebellum, SH-SY5Y and Human brain lysates; Mouse and Rat brain lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度
    Tissue culture supernatant
  • 克隆
    单克隆
  • 克隆编号
    EPR3497
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab109288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 60 kDa.
IP 1/10 - 1/100.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC or IHC-P.
  • 靶标

    • 功能
      Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission.
    • 序列相似性
      Contains 2 CUB domains.
      Contains 1 LDL-receptor class A domain.
    • 翻译后修饰
      N-glycosylated.
    • 细胞定位
      Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Brain specific transmembrane protein antibody
      • Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2 antibody
      • Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2 antibody
      • BTCL2 antibody
      • FLJ10430 antibody
      • FLJ14724 antibody
      • FLJ90456 antibody
      • NEOT2 antibody
      • NETO 2 antibody
      • Neto2 antibody
      • NETO2_HUMAN antibody
      • Neuropilin (NRP) and tolloid (TLL) like 2 antibody
      • Neuropilin and tolloid like protein 2 antibody
      • Neuropilin and tolloid-like protein 2 antibody
      see all

    Anti-NETO2 antibody [EPR3497] 图像

    • All lanes : Anti-NETO2 antibody [EPR3497] (ab109288) at 1/1000 dilution

      Lane 1 : Human cerebellum lysates
      Lane 2 : SH-SY5Y cell lysates
      Lane 3 : Human brain lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 60 kDa
    • All lanes : Anti-NETO2 antibody [EPR3497] (ab109288) at 1/1000 dilution

      Lane 1 : mouse brain lysates
      Lane 2 : rat brain lysates

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 60 kDa

    Anti-NETO2 antibody [EPR3497] (ab109288)参考文献

    This product has been referenced in:
    • Vernon CG & Swanson GT Neto2 assembles with kainate receptors in DRG neurons during development and modulates neurite outgrowth in adult sensory neurons. J Neurosci N/A:N/A (2017). WB . Read more (PubMed: 28235897) »
    • Hu L  et al. Upregulation of NETO2 expression correlates with tumor progression and poor prognosis in colorectal carcinoma. BMC Cancer 15:1006 (2015). WB ; Human . Read more (PubMed: 26699544) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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