Anti-Nestin抗体- Aminoterminal end (ab76684)

概述

  • 产品名称Anti-Nestin抗体- Aminoterminal end
    参阅全部 Nestin 一抗
  • 描述
    兔多克隆抗体to Nestin - Aminoterminal end
  • 经测试应用适用于: IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the N-terminal region of human Nestin conjugated to KLH

  • 阳性对照
    • Human breast carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab76684 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
ELISA 1/1000.

靶标

  • 功能Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
  • 组织特异性CNS stem cells.
  • 序列相似性Belongs to the intermediate filament family.
  • 发展阶段Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments.
  • 翻译后修饰Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ESTM 46 antibody
    • FLJ 21841 antibody
    • FLJ21841 antibody
    • Intermediate filament protein antibody
    • Nbla00170 antibody
    • nes antibody
    • NEST_HUMAN antibody
    • Nestin antibody
    see all

Anti-Nestin antibody - Aminoterminal end 图像

  • ab76684, at a 1/50 dilution, staining Nestin in formalin fixed, paraffin embedded human breast carcinoma tissue by Immunohistochemistry. A peroxidase conjugated secondary antibody was then used, followed by DAB staining.

Anti-Nestin antibody - Aminoterminal end (ab76684)参考文献

ab76684 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab76684.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"