概述

  • 产品名称Anti-NELF抗体
    参阅全部 NELF 一抗
  • 描述
    兔多克隆抗体to NELF
  • 特异性NELF recognises both the 263 aa and 528 aa isoform.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    A region within synthetic peptide: SDPTPMKADT SHDSRDSSDL QSSHCTLDEA FEDLDWDTEK GLEAVACDTE, corresponding to internal sequence amino acids 289-338 of Human NELF

  • 阳性对照
    • HepG2 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab58752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 5 µg/ml. Detects a band of approximately 29 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Couples NMDA receptor signaling to the nucleus. Influences outgrowth of olfactory axons and migration of LHRH neurons.
  • 组织特异性Highly expressed in adult and fetal brain, testis and kidney.
  • 疾病相关Defects in NELF may be associated with idiopathic hypogonadotropic hypogonadism (IHH) [MIM:146110]. IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function.
  • 细胞定位Cell membrane. Nucleus. Found on the outside of the LHRH cell membrane and axons projecting from the olfactory pit and epithelium. Myristoylation is a prerequisite for extranuclear localization.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Nasal embryonic LHRH factor antibody
    • Nasal embryonic luteinizing hormone releasing hormone factor antibody
    • Nasal embryonic luteinizing hormone-releasing hormone factor antibody
    • Nelf antibody
    • NELF_HUMAN antibody
    see all

Anti-NELF antibody 图像

Anti-NELF antibody (ab58752)参考文献

ab58752 has not yet been referenced specifically in any publications.

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