概述

  • 产品名称Anti-NEK9抗体
    参阅全部 NEK9 一抗
  • 描述
    兔多克隆抗体to NEK9
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide: GGGGGEEEDS QQESETPDPS GGFRGTMEAD RGMEGLISPT EAMGNSNGAS , corresponding to internal sequence amino acids 756-805 of Human NEK9 (NP_149107)

  • 阳性对照
    • THP-1 cell lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab89853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 107 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
  • 组织特异性Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.
  • 序列相似性Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
    Contains 1 protein kinase domain.
    Contains 6 RCC1 repeats.
  • 发展阶段Expression varied mildly across the cell cycle, with highest expression observed in G1 and stationary-phase cells.
  • 结构域Dimerizes through its coiled-coil domain.
  • 翻译后修饰Autophosphorylated on serine and threonine residues. When complexed with FACT, exhibits markedly elevated phosphorylation on Thr-210. During mitosis, not phosphorylated on Thr-210. Phosphorylated by CDK1 in vitro.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA1995 antibody
    • APUG antibody
    • DKFZp434D0935 antibody
    • LCCS10 antibody
    • MGC138306 antibody
    • MGC16714 antibody
    • NC antibody
    • NEK 9 antibody
    • Nek8 antibody
    • nek9 antibody
    • NEK9_HUMAN antibody
    • Nercc 1 kinase antibody
    • NERCC antibody
    • NERCC1 antibody
    • Nercc1 kinase antibody
    • Never in mitosis A related kinase 9 antibody
    • Never in mitosis A-related kinase 9 antibody
    • NIMA (never in mitosis gene a) related kinase 9 antibody
    • NIMA related kinase 8 antibody
    • NIMA related kinase 9 antibody
    • NIMA related kinase Nek8 antibody
    • NimA related protein kinase 9 antibody
    • NIMA-related kinase 8 antibody
    • NimA-related protein kinase 9 antibody
    • Serine/threonine protein kinase Nek9 antibody
    • Serine/threonine-protein kinase Nek9 antibody
    see all

Anti-NEK9 antibody 图像

  • Anti-NEK9 antibody (ab89853) at 1 µg/ml + THP-1 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 107 kDa

Anti-NEK9 antibody (ab89853)参考文献

ab89853 has not yet been referenced specifically in any publications.

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