RabMAb

Anti-NEK6抗体[EPR5282] (ab109177)

概述

  • 产品名称Anti-NEK6抗体[EPR5282]
    参阅全部 NEK6 一抗
  • 描述
    兔单克隆抗体[EPR5282] to NEK6
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human NEK6

  • 阳性对照
    • HepG2, HeLa, 293T and HT-1080 cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab109177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 36 kDa.
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Activated during M phase. Required for chromosome segregation at metaphase-anaphase transition and therefore for mitotic progression. Inhibition of activity results in apoptosis. Phosphorylates KIF11 to promote mitotic spindle formation.
    • 组织特异性Ubiquitous, with highest expression in heart and skeletal muscle.
    • 序列相似性Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
      Contains 1 protein kinase domain.
    • 翻译后修饰Autophosphorylated.
    • 细胞定位Cytoplasm. Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Highly similar to cell cycle protein kinase CDC5/MSD2 antibody
      • NEK6 antibody
      • NEK6_HUMAN antibody
      • Never in mitosis A-related kinase 6 antibody
      • NIMA (Never In Mitosis Gene A) Related Kinase 6 antibody
      • NimA related protein kinase 6 antibody
      • NimA-related protein kinase 6 antibody
      • Protein kinase SID6 1512 antibody
      • Protein kinase SID6-1512 antibody
      • Putative serine threonine protein kinase antibody
      • Serine/threonine protein kinase Nek6 antibody
      • Serine/threonine-protein kinase Nek6 antibody
      • SID6 1512 antibody
      • SID61512 antibody
      see all

    Anti-NEK6 antibody [EPR5282] 图像

    • All lanes : Anti-NEK6 antibody [EPR5282] (ab109177) at 1/1000 dilution

      Lane 1 : HepG2 lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : HT-1080 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 36 kDa

    Anti-NEK6 antibody [EPR5282] (ab109177)参考文献

    ab109177 has not yet been referenced specifically in any publications.

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