Anti-NEIL3抗体(ab110049)
Key features and details
- Rabbit polyclonal to NEIL3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-NEIL3抗体 -
描述
兔多克隆抗体to NEIL3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Synthetic peptide corresponding to Human NEIL3 (internal sequence).
-
阳性对照
- WB: COLO, HuvEc, HepG2 and HeLa cell extracts.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab110049于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 68 kDa.
|
说明 |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 68 kDa. |
靶标
-
功能
Reports about DNA glycosylase activity are contradictory. A number of references report finding no DNA glycosylase activity and the protein lacks a proline residue at the N-terminus which functions as an active site residue in other members of the FPG family. However, the mouse ortholog has been shown to have both DNA glycosylase and AP lyase activities and PubMed:19170771 demonstrates AP lyase activity. Prefers single-stranded DNA or partially single-stranded DNA structures such as bubble and fork structures to double-stranded DNA in vitro. Displays a broad recognition spectrum, preferring FapyA and FapyG followed by 5-OHU, 5-PHC and 5-OHMH and then Tg and 8-oxoA. No activity on 8-oxoG detected. -
组织特异性
Detected in thymus and testis. Expressed at higher levels in tumor tissue than in the corresponding normal tissues except for pancreas and testis where expression is higher in normal than tumor tissue. -
序列相似性
Belongs to the FPG family.
Contains 1 FPG-type zinc finger.
Contains 1 RanBP2-type zinc finger. -
细胞定位
Nucleus. - Information by UniProt
-
数据库链接
- Entrez Gene: 55247 Human
- Entrez Gene: 234258 Mouse
- Omim: 608934 Human
- SwissProt: Q8TAT5 Human
- SwissProt: Q8K203 Mouse
- Unigene: 405467 Human
- Unigene: 281749 Mouse
-
别名
- 123 antibody
- AI449477 antibody
- BC034753 antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab110049 尚未被引用在任何文献中。