Anti-NEIL2抗体(ab56577)

概述

  • 产品名称Anti-NEIL2抗体
    参阅全部 NEIL2 一抗
  • 描述
    小鼠单克隆抗体to NEIL2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-333 of Human NEIL2

性能

应用

Our Abpromise guarantee covers the use of ab56577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
    • 组织特异性Detected in testis, skeletal muscle, heart, brain, placenta, lung, pancreas, kidney and liver.
    • 序列相似性Belongs to the FPG family.
      Contains 1 FPG-type zinc finger.
    • 结构域The zinc-finger domain is important for DNA binding.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DNA glycosylase/AP lyase Neil2 antibody
      • DNA-(apurinic or apyrimidinic site) lyase Neil2 antibody
      • Endonuclease 8-like 2 antibody
      • Endonuclease VIII-like 2 antibody
      • NEH2 antibody
      • Nei endonuclease VIII like 2 (E. coli) antibody
      • Nei endonuclease VIII like 2 antibody
      • Nei homolog 2 antibody
      • Nei-like 2 antibody
      • Nei-like protein 2 antibody
      • NEI2 antibody
      • NEIL2 antibody
      • NEIL2_HUMAN antibody
      see all

    Anti-NEIL2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56577 NEIL2 antibody at 1ug/ml. Predicted band size of immunogen is 63 kDa

    Anti-NEIL2 antibody (ab56577)参考文献

    ab56577 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry and your interest in our products. The tag such as glutathione-S-transferase (GST) is often used for proteins for expression and purification applications. GST tag is a 26 kDa protein which is attached to the NEIL2 recom...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"