概述

  • 产品名称
  • 描述
    兔多克隆抗体to NDUFV1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 218 and 429 of Human NDUFV1

  • 阳性对照
    • HepG2 whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab96227 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 51 kDa.

靶标

  • 功能
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
  • 疾病相关
    Defects in NDUFV1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
    Defects in NDUFV1 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
  • 序列相似性
    Belongs to the complex I 51 kDa subunit family.
  • 细胞定位
    Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CI 51kD antibody
    • CI-51kD antibody
    • CI51KD antibody
    • Complex I 51kD antibody
    • Complex I-51kD antibody
    • FLJ59059 antibody
    • mitochondrial antibody
    • NADH dehydrogenase (ubiquinone) flavoprotein 1 antibody
    • NADH dehydrogenase [ubiquinone] flavoprotein 1 antibody
    • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial antibody
    • NADH dehydrogenase flavoprotein 1 antibody
    • NADH ubiquinone oxidoreductase 51 kDa subunit antibody
    • NADH ubiquinone oxidoreductase antibody
    • NADH ubiquinone oxidoreductase core subunit V1 antibody
    • NADH-ubiquinone oxidoreductase 51 kDa subunit antibody
    • NDUFV 1 antibody
    • ndufv1 antibody
    • NDUV1_HUMAN antibody
    • UQOR1 antibody
    see all

图片

  • Anti-NDUFV1 antibody (ab96227) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 51 kDa

实验方案

文献

ab96227 has not yet been referenced specifically in any publications.

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