概述

  • 产品名称Anti-NDUFA1抗体
    参阅全部 NDUFA1 一抗
  • 描述
    小鼠单克隆抗体to NDUFA1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant full length protein: MWFEILPGLS VMGVCLLIPG LATAYIHRFT NGGKEKRVAH FGYHWSLMER DRRISGVDRY YVSKGLENID , corresponding to amino acids 24-71 of Human NDUFA1

性能

应用

Our Abpromise guarantee covers the use of ab55511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    • 组织特异性Primarily expressed in heart and skeletal muscle.
    • 疾病相关Defects in NDUFA1 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
    • 序列相似性Belongs to the complex I NDUFA1 subunit family.
    • 细胞定位Mitochondrion inner membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CI MWFE antibody
      • CI-MWFE antibody
      • Complex I MWFE antibody
      • complex I MWFE subunit antibody
      • Complex I-MWFE antibody
      • MWFE antibody
      • MWFE, B. taurus, homolog of antibody
      • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa antibody
      • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 antibody
      • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 antibody
      • NADH oxidoreductase subunit MWFE antibody
      • NADH ubiquinone oxidoreductase (complex 1) antibody
      • NADH ubiquinone oxidoreductase MWFE subunit antibody
      • NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 1 antibody
      • NADH-ubiquinone oxidoreductase MWFE subunit antibody
      • NDUA1_HUMAN antibody
      • NDUFA 1 antibody
      • NDUFA1 antibody
      • Type I dehydrogenase antibody
      • ZNF 183 antibody
      • ZNF183 antibody
      see all

    Anti-NDUFA1 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab55511 NDUFA1 antibody at 1ug/ml. Predicted band size of immunogen is 31 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-NDUFA1 antibody (ab55511)参考文献

    ab55511 has not yet been referenced specifically in any publications.

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