概述

  • 产品名称Anti-NDUF3抗体
  • 描述
    兔多克隆抗体to NDUF3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    LLEPRIEIVV VGTGDRTERL QSQVLQAMRQ RGIAVEVQDT PNACATFNFL CHEGRVTGAA LIPPPGGTSL TSLGQAAQ, corresponding to amino acids 107-184 of Human NDUF3

  • 阳性对照
    • RT-4, U-251 MG, Human liver and tonsil lysate. Human duodenum tissue

性能

应用

Our Abpromise guarantee covers the use of ab122270 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/250 - 1/500.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
  • 疾病相关Defects in NDUFAF3 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
  • 细胞定位Nucleus. Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C3orf60 antibody
    • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 antibody
    • NDUF3_HUMAN antibody
    • ndufaf3 antibody

Anti-NDUF3 antibody 图像

  • All lanes : Anti-NDUF3 antibody (ab122270) at 1/250 dilution

    Lane 1 : RT-4 lysate
    Lane 2 : U251 -MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate
  • ab122270, at 1/50 dilution, staining NDUF3 in Paraffin-embedded Human duodenum tissue by Immunohistochemistry.

Anti-NDUF3 antibody (ab122270)参考文献

ab122270 has not yet been referenced specifically in any publications.

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