概述

  • 产品名称Anti-NDRG2抗体
    参阅全部 NDRG2 一抗
  • 描述
    山羊多克隆抗体to NDRG2
  • 特异性ab113439 is expected to recognize reported isoform a (NP_963293.1) only. Reported variants represent identical protein: NP_963831.1, NP_963293.1, NP_963834.1, NP_963833.1.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Horse, Dog
  • 免疫原

    Synthetic peptide corresponding to Human NDRG2 aa 25-39 (N terminal).
    Sequence:

    KEAELAARILLDQGQ-C


    Database link: Q9UN36

  • 阳性对照
    • Human Brain (Temporal Cortex), Mouse and Rat Brain lysates

性能

应用

Our Abpromise guarantee covers the use of ab113439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:16,000.

WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).

靶标

  • 功能May be involved in dendritic cell and neuron differentiation. May have anti-tumor activity.
  • 组织特异性Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
  • 序列相似性Belongs to the NDRG family.
  • 发展阶段Specifically expressed during dendritic cell differentiation (in vitro). Expression is low in fetal brain and increases during brain postnatal development.
  • 细胞定位Cytoplasm. Cytoplasm > perinuclear region. Perinuclear in neurons.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Antidepressant related protein ADRG123 antibody
    • Cytoplasmic protein Ndr1 antibody
    • DKFZp781G1938 antibody
    • FLJ25522 antibody
    • KIAA1248 antibody
    • N myc downstream regulated gene 2 antibody
    • N myc downstream regulator 2 antibody
    • NDR1 related protein NDR2 antibody
    • NDRG 2 antibody
    • NDRG family member 2 antibody
    • NDRG1 related protein antibody
    • NDRG2 antibody
    • NDRG2_HUMAN antibody
    • Protein NDRG2 antibody
    • Protein Syld709613 antibody
    • SYLD antibody
    • Syld709613 protein antibody
    see all

Anti-NDRG2 antibody 图像

  • All lanes : Anti-NDRG2 antibody (ab113439) at 0.3 µg/ml

    Lane 1 : Mouse Brain lysate
    Lane 2 : Rat Brain lysate

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 41 kDa
  • Anti-NDRG2 antibody (ab113439) at 0.1 µg/ml + Human Temporal Cortex lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 41 kDa

Anti-NDRG2 antibody (ab113439)参考文献

ab113439 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113439.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"