概述

  • 产品名称Anti-NCR1抗体[n1D9]
    参阅全部 NCR1 一抗
  • 描述
    小鼠单克隆抗体[n1D9] to NCR1
  • 经测试应用适用于: ELISA, Flow Cyt, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 22-255 of Human NCR1

  • 阳性对照
    • Human peripheral blood mononuclear cells or natural killer cells.

性能

应用

Our Abpromise guarantee covers the use of ab14823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: 46 kDa.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
  • 组织特异性Selectively expressed by both resting and activated NK cells.
  • 序列相似性Belongs to the natural cytotoxicity receptor (NCR) family.
    Contains 2 Ig-like (immunoglobulin-like) domains.
  • 翻译后修饰N-glycosylated.
    O-glycosylated.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Activating NK receptor NK p46 antibody
    • CD335 antibody
    • FLJ99094 antibody
    • hNKp46 antibody
    • Ly94 antibody
    • Lymphocyte antigen 94 antibody
    • Lymphocyte antigen 94 homolog (activating NK receptor; NK p46) antibody
    • Lymphocyte antigen 94 homolog antibody
    • Natural cytotoxicity triggering receptor 1 antibody
    • Natural killer cell p46-related protein antibody
    • NCR1 antibody
    • NCT1 antibody
    • NCTR1_HUMAN antibody
    • NK cell activating receptor antibody
    • NK cell-activating receptor antibody
    • NK-p46 antibody
    • NKp46 antibody
    see all

Anti-NCR1 antibody [n1D9] 图像

  • ab14823 staining human PBMC by flow cytometry.

Anti-NCR1 antibody [n1D9] (ab14823)参考文献

This product has been referenced in:
  • Ascierto ML  et al. Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients. J Transl Med 11:145 (2013). IHC-P . Read more (PubMed: 23758773) »

See 1 Publication for this product

Product Wall


Unfortunately, we can not offer a blocking peptide for anti-NCR1 antibody [n1D9] (ab14823), since a recombinant full length protein corresponding to amino acids 22-255 of Human NCR1 was used as immunogen.


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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"