概述

  • 产品名称Anti-NCR1抗体[n1D9]
    参阅全部 NCR1 一抗
  • 描述
    小鼠单克隆抗体[n1D9] to NCR1
  • 经测试应用适用于: ELISA, Flow Cyt, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 22-255 of Human NCR1

  • 阳性对照
    • Human peripheral blood mononuclear cells or natural killer cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.08% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明Purified from mouse ascitic fluid by protein G affinity chromatography.
  • 克隆单克隆
  • 克隆编号n1D9
  • 骨髓瘤Sp2/0
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: 46 kDa.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
  • 组织特异性Selectively expressed by both resting and activated NK cells.
  • 序列相似性Belongs to the natural cytotoxicity receptor (NCR) family.
    Contains 2 Ig-like (immunoglobulin-like) domains.
  • 翻译后修饰N-glycosylated.
    O-glycosylated.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Activating NK receptor NK p46 antibody
    • CD335 antibody
    • FLJ99094 antibody
    • hNKp46 antibody
    • Ly94 antibody
    • Lymphocyte antigen 94 antibody
    • Lymphocyte antigen 94 homolog (activating NK receptor; NK p46) antibody
    • Lymphocyte antigen 94 homolog antibody
    • Natural cytotoxicity triggering receptor 1 antibody
    • Natural killer cell p46-related protein antibody
    • NCR1 antibody
    • NCT1 antibody
    • NCTR1_HUMAN antibody
    • NK cell activating receptor antibody
    • NK cell-activating receptor antibody
    • NK-p46 antibody
    • NKp46 antibody
    see all

Anti-NCR1 antibody [n1D9] 图像

  • ab14823 staining human PBMC by flow cytometry.

Anti-NCR1 antibody [n1D9] (ab14823)参考文献

This product has been referenced in:
  • Ascierto ML  et al. Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients. J Transl Med 11:145 (2013). IHC-P . Read more (PubMed: 23758773) »

See 1 Publication for this product

Product Wall


Unfortunately, we can not offer a blocking peptide for anti-NCR1 antibody [n1D9] (ab14823), since a recombinant full length protein corresponding to amino acids 22-255 of Human NCR1 was used as immunogen.


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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"