概述

  • 产品名称
  • 描述
    兔多克隆抗体to NCKX2
  • 特异性
    Detects rat sodium / calcium - potassium exchanger (NCKX 2) overexpressed in HEK cells transfected with the rat gene. By Western blot, the NCX2 antibody detects the recombinant rat protein (78kDa). Immunohistochemical staining of rat NCX2 in HEK cells transfected with the rat gene results in staining of the plasma membrane.
  • 经测试应用
    适用于: WB, IP, ICC/IF, IHC-Frmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Rat NCKX2 aa 90-102 (extracellular).
    Sequence:

    DLNDKIRDYTPQP


    (Peptide available as ab5896)

性能

应用

Our Abpromise guarantee covers the use of ab3507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100. Predicted molecular weight: 74 kDa.Can be blocked with NCKX2 peptide (ab5896).
IP Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IHC-Fr 1/100.

靶标

  • 功能
    Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
  • 序列相似性
    Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Na(+)/K(+)/Ca(2+) exchange protein 2 antibody
    • Na(+)/K(+)/Ca(2+)-exchange protein 2 antibody
    • NCKX 2 antibody
    • NCKX2_HUMAN antibody
    • OTTHUMP00000045115 antibody
    • Retinal cone Na Ca+K exchanger antibody
    • Retinal cone Na-Ca+K exchanger antibody
    • Slc24a2 antibody
    • Sodium/potassium/calcium exchanger 2 antibody
    • Solute carrier family 24 (sodium/potassium/calcium exchanger) member 2 antibody
    • Solute carrier family 24 member 2 antibody
    see all

Anti-NCKX2 antibody 图像

  • ab3507 staining NCKX2 in Rat brain tissue section by Immunohistochemistry (Frozen sections).



  • Predicted band size : 74 kDa

    Western blot detection of NCKX2 in Rat brain using ab3507.

Anti-NCKX2 antibody (ab3507)参考文献

ab3507 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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