GPCRs are the largest family of membrane proteins in the human genome. They are coupled to intracellular signaling pathways via a G protein, which can lead to alterations in the production of various intracellular second messengers. Popular receptor targets include glutamate, GABA and receptor kinases which may lead to the alteration of intracellular proteins including PI3K/Akt, PKC and many more.
Transporters allow for the passage of ions, small molecules and peptides across a lipid bilayer, which displays selective membrane permeability. Popular types include neurotransmitter, glucose and ion channel transporters. Join researchers worldwide and find receptor and transporter agonists and antagonists for your research.