Natural大鼠Plasmin protein (ab92813)

概述

描述

  • 性质Natural
  • 来源Native
  • 氨基酸序列
    • 种属Rat

技术指标

Our Abpromise guarantee covers the use of ab92813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性 Activity: 100% by definition (eluted from SBTI) 1 ug of plasmin corresponds to 0.024 CU or to 0.028 CTA-U.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Prepared from plasminogen by activation with immobilized Human uPA.
  • 形式Liquid
  • 补充说明Spectrophotometric Data: Ultraviolet: Absorbance (280nm) = 4.5 Epsilon 0.1% = 1.69 Active Concentration = 2.66 mg/mL
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1M Sodium chloride, 0.1M HEPES, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Plasminogen
    • PLG
  • 相关性Plasmin is an enzyme formed in the circulating blood, and many other extracellular fluids, from the zymogen plasminogen. Plasminogen is a single-chain glycoprotein with 790 amino acid residues. Activation to the active form, plasmin, by urokinase involves cleavage at the arg-val bond between residues 560 and 561, resulting in the formation of the 2-chain plasmin molecule held together by 2 disulfide linkages. The heavier chain contains about 411 residues and the lighter chain about 233. The main function of plasmin is the digestion of fibrin in blood clots. Plasmin is a proteolytic enzyme with a specificity similar to that of trypsin. Like trypsin, plasmin belongs to the family of serine proteinases, in which the active site catalytic triad, his-57, asp-102, and ser-195 (chymotrypsin numbering), is situated in the light chain. Plasmin acts as a proteolytic factor in a variety of processes other than fibrinolysis; including embryonic development, tissue remodelling, tumour invasion and inflammation; in ovulation it weakens the walls of the Graafian follicle. A Deficiency of plasmin may lead to thrombosis, as clots are not degraded adequately.
  • 细胞定位Secreted

Natural rat Plasmin protein 图像

  • 10% SDS-PAGE analysis of ab92813
    Lane 1: ab92813 (3µg) Reduced
    Lane 2: ab92813 (3µg) + Antiplasmin (10µg) Reduced
    Lane 3: ab92813 (3µg) Non-reduced
    Lane 4: ab92813 (3µg) + Antiplasmin (10µg) Non-reduced
    Lane 5: Molecular weight markers

Natural rat Plasmin protein (ab92813)参考文献

ab92813 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab92813.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"