Natural小鼠NGF protein (ab69757)

概述

描述

  • 性质Natural
  • 来源Native
  • 氨基酸序列
    • 种属Mouse
    • 序列SSTHPVFHMGEF SVCDSVSVWV GDKTTATDIK GKEVTVLAEV NINNSVFRQY FFETKCRASN PVESGCRGID SKHWNSYCTT THTFVKALTT DEKQAAWRFI RIDTACVCVL SRKATRRG
    • 分子量13 kDa
    • 氨基酸122 to 241
    • 额外的序列信息NGF beta Mouse produced in Submaxillary Gland of Grown Mouse is a homodimer, non-glycosylated, polypeptide chain containing 2 identical 120 amino acids.

相关产品

技术指标

Our Abpromise guarantee covers the use of ab69757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purity: greater than 98% as determined by: analysis by RP-HPLC and analysis by SDS-PAGE.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 5% Mannitol and 1% HSA

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute in sterile 18MOhms/cm water, to not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

常规信息

  • 别名
    • Beta nerve growth factor
    • Beta NGF
    • Beta-nerve growth factor
    • Beta-NGF
    • HSAN5
    • MGC161426
    • MGC161428
    • Nerve growth factor
    • Nerve growth factor (beta polypeptide)
    • Nerve growth factor beta
    • Nerve growth factor beta polypeptide
    • Nerve growth factor beta subunit
    • NGF
    • NGF_HUMAN
    • NGFB
    • NID67
    see all
  • 功能Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
  • 疾病相关Neuropathy, hereditary sensory and autonomic, 5
  • 序列相似性Belongs to the NGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt

Natural mouse NGF protein (ab69757)参考文献

ab69757 has not yet been referenced specifically in any publications.

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