Anti-Natural Killer Cell Activation Structures抗体[ANK61] (ab36392)


  • 产品名称Anti-Natural Killer Cell Activation Structures抗体[ANK61]
  • 描述
    小鼠单克隆抗体[ANK61] to Natural Killer Cell Activation Structures
  • 特异性The antigen recognized by ab36392 is highly expressed on freshly isolated and cultured NK cells. The antibody also binds to rat alpha beta TCR T cells and at a low level to B cells.
  • 经测试应用适用于: Flow Cyt, IP, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Cell preparation of IL 2 activated cultured NK cells (Wag rats)

  • 常规说明

    Triggering of the antigen by ab36392 antibody activates the lytic machinery of rat NK cells, but not of T cells.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: Tissue culture supernatant
  • 纯度Tissue culture supernatant
  • Primary antibody说明Triggering of the antigen by ab36392 antibody activates the lytic machinery of rat NK cells, but not of T cells.
  • 克隆单克隆
  • 克隆编号ANK61
  • 同种型IgG1
  • 研究领域


Our Abpromise guarantee covers the use of ab36392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Use at an assay dependent concentration.

IHC-P Use at an assay dependent concentration.

Use at an assay dependent concentration.


  • 相关性Natural killer cells (NK) are a type of lymphocyte and a component of innate immune defense. They share a common progenitor with T cells and have been described as large, granular, bone-marrow derived lymphocytes. These cells do not destroy the attacking microorganisms directly; they attack infected cells and cells that appear that they might be cancer. NK cells are not phagocytic; they weaken the target cell's plasma membrane, causing water and ions to diffuse into the cell and expanding it. Under this large pressure, the target cell lyses. NK cells are characterised immunohistochemically by the presence of CD56 and the absence of CD3 on the cell membrane. NK cells are activated in response to interferons or macrophage-derived cytokines. They serve to contain virus infections while the adaptive immune response is generating antigen specific cytotoxic T cells that can clear the infection. Patients deficient in NK cells prove to be highly susceptible to early phases of herpes virus infection.

Anti-Natural Killer Cell Activation Structures antibody [ANK61] (ab36392)参考文献

ab36392 has not yet been referenced specifically in any publications.

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There may be some antibodies where I might have suggested the human tissues or cells. I apologize for this. I have included the positive control information irrespective of species so similar mouse tissues sections ca...

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The positive control for ab36392 is IL2 activatedcultured NK cells.

ab9918; human tonsil sections, human cervical squamous cell carcinoma section

ab34674; human artery or colon tissue sections
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Thank you forhaving your customercomplete our questionnaire. I am sorry to hear that these antibodies are not providing satisfactory results for them. The details provided will enable us to investigate this case and will provide us with vital informati...

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