Natural人Transferrin protein (ab77932)

概述

描述

  • 性质
    Native
  • 来源
    Native
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab77932 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Iron content: >1.0ug/mg protein. Total Iron Binding Capacity: 1.2-1.6ug/mg
  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Lyophilised
  • 补充说明
    Iron content: >1.0ug/mg protein. Total Iron Binding Capacity: 1.2-1.6ug/mg
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM PBS, 150mM Sodium chloride, pH 7.4

  • 复溶
    Reconstitute with 1.31ml distilled water.

常规信息

  • 别名
    • Apotransferrin
    • Beta 1 metal binding globulin
    • Beta-1 metal-binding globulin
    • DKFZp781D0156
    • PRO1400
    • PRO1557
    • PRO2086
    • Serotransferrin
    • Serotransferrin precursor
    • Siderophilin
    • TF
    • TFQTL1
    • Transferin
    • Transferrin
    • TRFE_HUMAN
    see all
  • 功能
    Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
  • 组织特异性
    Expressed by the liver and secreted in plasma.
  • 疾病相关
    Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
  • 序列相似性
    Belongs to the transferrin family.
    Contains 2 transferrin-like domains.
  • 细胞定位
    Secreted.
  • Information by UniProt

文献

ab77932 has not yet been referenced specifically in any publications.

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