Natural人TIMP2 protein (ab39314)

概述

描述

  • 性质Natural
  • 来源Native
  • 氨基酸序列 1
    • 种属Human
    氨基酸序列 2
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab39314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

  • 纯度> 95 % SDS-PAGE.
    TIMP2 is purified from human fibroblasts, and is essentially free of contaminating MMPs or other known TIMPs.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, PBS, pH 7.4

常规信息

  • 别名
    • CSC 21K
    • CSC-21K
    • CSC21K
    • Metalloproteinase inhibitor 2
    • Metalloproteinase inhibitor 2 precursor
    • TIMP 2
    • TIMP metallopeptidase inhibitor 2
    • TIMP-2
    • TIMP2
    • TIMP2_HUMAN
    • Tissue Inhibitor of Metalloproteinase 2
    • Tissue inhibitor of metalloproteinases 2
    see all
  • 功能Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
  • 序列相似性Belongs to the protease inhibitor I35 (TIMP) family.
    Contains 1 NTR domain.
  • 翻译后修饰The activity of TIMP2 is dependent on the presence of disulfide bonds.
  • 细胞定位Secreted.
  • Information by UniProt

Natural Human TIMP2 protein (ab39314)参考文献

ab39314 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam.
The molecular weight of ab39314 is 24,398g/mol and the extinction co-efficient is 33160cm-1M-1. Unfortunately I do not have any information on its use for titration of mmp14
If there is anything else I can help...

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