Natural人IgM Kappa protein (ab99015)

概述

  • 产品名称
    Natural人IgM Kappa protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Native
  • 来源
    Native
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 分子量
      49 kDa
    • 氨基酸
      1 to 452

技术指标

Our Abpromise guarantee covers the use of ab99015 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Liquid
  • 补充说明
    Starting material tested and found negative for HIV I & II antibodies, Hepatits B surface antigen and Hepatitis C antibodies.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: 0.2M Sodium chloride, 50mM Tris, pH 8.0

常规信息

  • 别名
    • Ig mu chain C region
    • IGHM
  • 相关性
    IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as 'natural' blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences. Immunoglobulin (Ig) molecules consist of two chains, one heavy chain (which can be alpha, delta, epsilon, gamma or mu) and one light chain (which can be kappa or lambda) each consisting of a variable and a constant region. An IgM molecule contains thus a mu heavy chain combined with either a kappa or a lambda light chains. It is found almost exclusively as an homopentamer in the serum. Membrane-bound IgM molecules are non-covalently associated with heterodimer of CD79A and CD79B.
  • 细胞定位
    Isoform 1: Secreted. Isoform 2: Cell membrane; Single-pass type I membrane protein.

文献

ab99015 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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