Natural人IgG4 protein (ab90286)



  • 性质Natural
  • 来源Native
  • 氨基酸序列
    • 种属Human


Our Abpromise guarantee covers the use of ab90286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests.
  • 应用


  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • 补充说明

    IgG4 from human myeloma plasma. MW: 146,000.

    Protein Determination: Extinction Coefficient (E) 0.1% at 280nm =1.36.

    Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests.

  • Concentration information loading...


  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: 20mM PBS, 150mM Sodium chloride, pH 7.4


  • 别名
    • Ig gamma 4 chain C region
    • IGHG4
    • Immunoglobulin heavy constant gamma 4 (G4m marker)
    • MGC117419
  • 相关性IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with recurrent pyogenic infections.
  • 细胞定位Secreted

Natural Human IgG4 protein 图像

  • SDS-PAGE analysis of Active human IgG4 full length protein (ab90286).

    1. IgG4 - 5 μg (reduced / heated)

    2. IgG4 - 10 μg (reduced / heated)

    3. IgG4 - 20 μg (reduced / heated)

    4. IgG4 - 5 μg (non-reduced / no heat)

    5. IgG4 - 10 μg (non-reduced / no heat)

    6. IgG4 - 20 μg (non-reduced / no heat)

Natural Human IgG4 protein (ab90286)参考文献

ab90286 has not yet been referenced specifically in any publications.

Product Wall

Neither of these proteins are recombinant. They are isolated from myeloma plasma, identified as IgG1 and IgG4 myelomas.

These products are tested for possible contaminating IgGs by ELISA. Each of these products is at least 95% pure and by ELI...

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IgG4 is a complete immunoglobulin in that it has 2 heavy chains and 2 light chains per molecule. However, this is a myeloma which means that every molecule contains either Lambda Light chain or Kappa Light Chain; not both like would be found in a ...

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Vielen Dank für Ihren Anruf.

Ich habe nun die Antwort aus dem Labor erhalten, und Sie sollten ohne Probleme dieses Produkt als Positivekontrolle im ELISA einsetzen können:

"Yes, you may use this product as a positive...

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The product ab90286 has kappa light chain however ab98893 has lamda light chain.

The proteins are dissolved in different storage buffer and the concentration is different.

These product are from ...

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The protein has a Kappa Light Chain.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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I am happy to check these concentrations for you. Please find here below the answers:

IgG1 protein (ab90283) you will receive 1 mg at 3.41mg/ml, ¨so it will be in 293ul

IgG2 protein...

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Thank you for contacting us with your question.

We don't assign specific expiration dates to our products (most haven't been tested for an exact date) but we are able to guarantee the protein for up to 6 months after purchase.

I hop...

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Vielen Dank für Ihre Anfrage.

Da es sich hier um ein inaktives Protein handelt, kann es bis zu einer Woche bei 4C gelagert werden. Da dem Protein kein Glycerin zugesetzt wurde, sollte eine Lagerung bei -40 oder -80C nichts im Wege...

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Thank you for your enquiry.

We do not have set expiration dates for our products. Most antibodies and proteinsare stable and can last for anywhere from a few months to several years if stored properly, so we strongly recommend that you follo...

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Unfortunately this is not a product that we carry at this time. The Fc region may be cleaved from F(ab) region with papain or pepsin and purified out but this assay would have to be worked out experimentally. Read More