Native人IgA1蛋白(ab91020)
Key features and details
- Expression system: Native
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
描述
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产品名称
Native人IgA1蛋白 -
生物活性
No reaction by IEP to IgA2 antiserum. -
纯度
> 95 % SDS-PAGE. -
表达系统
Native -
蛋白长度
Full length protein -
无动物成分
No -
性质
Native -
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种属
Human -
预测分子量
160 kDa
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技术指标
Our Abpromise guarantee covers the use of ab91020 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
补充说明
Protein Determination: Extinction Coefficient (E) 0.1% at 280nm, 1cm pathway = 1.32. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.No reaction by IEP to IgA2 antiserum. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -20°C.
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.0268% PBS, 0.87% Sodium chloride
常规信息
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别名
- Ig alpha 1 chain C region
- IGHA1
- immunoglobulin heavy constant alpha 1
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相关性
Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. -
细胞定位
Secreted
图片
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SDS-PAGE: 4-12% Bis-Tris NuPAGE gel
1. 5 μg Human IgA1 (reduced /heated)
2. 10 μg Human IgA1 (reduced/ heated)
3. 20 μg Human IgA1 (reduced/ heated)
4. Molecular weight markers
5. 5 μg Human IgA1 (non-reduced/no heat)
6. 10 μg Human IgA1 (non-reduced/no heat)
7. 20 μg Human IgA1 (non-reduced/no heat)
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab91020 被引用在 6 文献中.
- Zhu X et al. Liuwei Dihuang Pills Inhibit Podocyte Injury and Alleviate IgA Nephropathy by Directly Altering Mesangial Cell-Derived Exosome Function and Secretion. Front Pharmacol 13:889008 (2022). PubMed: 35899112
- Yu M et al. Mesangial Cell-Derived Exosomal miR-4455 Induces Podocyte Injury in IgA Nephropathy by Targeting ULK2. Oxid Med Cell Longev 2022:1740770 (2022). PubMed: 36388165
- Sánchez-Salguero E et al. Maternal IgA2 Recognizes Similar Fractions of Colostrum and Fecal Neonatal Microbiota. Front Immunol 12:712130 (2021). PubMed: 34804008
- Xia M et al. Based on Network Pharmacology Tools to Investigate the Mechanism of Tripterygium wilfordii Against IgA Nephropathy. Front Med (Lausanne) 8:794962 (2021). PubMed: 34977095
- Zheng N et al. TLR7 in B cells promotes renal inflammation and Gd-IgA1 synthesis in IgA nephropathy. JCI Insight 5:N/A (2020). PubMed: 32699192
- Sánchez-Salguero E et al. Infectious episodes during pregnancy, at particular mucosal sites, increase specific IgA1 or IgA2 subtype levels in human colostrum. Matern Health Neonatol Perinatol 5:9 (2019). PubMed: 31205733