Natural人Gamma Thrombin protein (ab81592)

概述

  • 产品名称Natural人Gamma Thrombin protein
  • 蛋白长度Full length protein

描述

  • 性质Natural
  • 来源Native
  • 氨基酸序列
    • 种属Human
    • 氨基酸328 to 622

技术指标

Our Abpromise guarantee covers the use of ab81592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性<1% Thrombin activity. Specific activity is determined by Fibrinogen clotting assay relative to NIH standard thrombin. 1 NIH Unit = 1.15 IS Units
  • 应用

    Functional Studies

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 6.50
    Constituents: 0.1% Polyethylene glycol, 1.64% Sodium phosphate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Activation peptide fragment 1
    • Activation peptide fragment 2
    • Cf 2
    • Cf2
    • Coagulation factor II
    • Coagulation factor II (thrombin)
    • FII
    • Prepro coagulation factor II
    • Prothrombin
    • Prothrombin B chain
    • PT
    • RP23-176N9.4
    • RPRGL2
    • Serine protease
    • THPH1
    • Thrombin heavy chain
    • Thrombin light chain
    see all
  • 相关性Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of thrombin. Gamma Thrombin is a proteolyzed form of Alpha Thrombin. Gamma Thrombin consists of four chains (A, B1, B5, B4) with a disulfide link between the A peptide and the B5 peptide.
  • 细胞定位Secreted, extracellular space.

Natural human Gamma Thrombin protein (ab81592)参考文献

ab81592 has not yet been referenced specifically in any publications.

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