Natural人Carcino Embryonic Antigen CEA protein (ab2282)

概述

描述

  • 性质Natural
  • 来源Native
  • 氨基酸序列
    • 种属Human
    • 分子量76 kDa
    • 额外的序列信息The source is single patient source colon carcinoma liver metastatic tissue. Blood sample from the tissue donors was tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, and HCV.

技术指标

Our Abpromise guarantee covers the use of ab2282 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 形式Liquid
  • 补充说明

    Blood sample from the tissue donors was tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV.

     

    Applications: CEA can be used as general marker in screening and monitoring malignant disease states. CEA is suitable as immunogen for antisera production, tracer for iodination, standard for immunoassay. As preparation is mitogen free it is also suitable for in vitro and in vivo studies of specific immune response (vaccine trials).

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituent: 0.268% PBS

    sterile, preservative free

常规信息

  • 别名
    • Carcinoembryonic antigen
    • Carcinoembryonic antigen-related cell adhesion molecule 5
    • CD66e
    • CEA
    • Ceacam5
    • CEAM5_HUMAN
    • DKFZp781M2392
    • Meconium antigen 100
    • OTTHUMP00000199032
    • OTTHUMP00000199033
    • OTTHUMP00000199034
    see all
  • 功能Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
  • 组织特异性Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
  • 序列相似性Belongs to the immunoglobulin superfamily. CEA family.
    Contains 7 Ig-like (immunoglobulin-like) domains.
  • 翻译后修饰Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
  • 细胞定位Cell membrane.
  • Information by UniProt

Natural Human Carcino Embryonic Antigen CEA protein (ab2282)参考文献

ab2282 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. I can confirm that all the products you chose are suitable for a CEA human sandwich ELISA and that ab2282 is also a suitable standard/ positive control. I can also confirm that ab2282 is obtained from a single patien...

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Thank you for your enquiry. Protein concentration determination of CEA Ag is not possible with for example BCA method (Pierce) because of high degree of glycosylation of the protein. The glycosylation decreases protein concentration measured by comm...

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Thank you for your enquiry. Following correspondence with the lab I have ascertained that Carcino Embryonic Antigen CEA protein (ab2282) is at least 95% pure and is purified by immunoaffinity purification. I hope this information helps, please ...

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Thank you for your enquiry, we do not know the extinction coefficient but I can provide the protein sequence of the precursor protein from the SwissProt database. Please find the link below: http://us.expasy.org/cgi-bin/niceprot.pl?P06731 I hope...

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Thank you for your enquiry. The mitogen free CEA that we are offering is filtered and sterile. The sterility of CEA is tested by growth on thioglycollate medium.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"