Natural人Apotransferrin protein (ab91100)

概述

描述

  • 性质
    Native
  • 来源
    Native
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab91100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.
    Iron Content: <30 µg per gram. Purified to have less than 0.01% iron and an iron-binding capacity of 1.25 ug/mg. Sterile filtered using 0.2 micron filter.
  • 形式
    Lyophilised
  • 补充说明
    Endotoxin Level: <0.1 Eu per mg by LAL testing. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20ºC.

    Preservative: None
    Constituents: 10mM Sodium phosphate, pH 7.4

  • 复溶
    Dissolves in water at 10 mg per ml.

常规信息

  • 别名
    • apo transferrin
    • apo-transferrin
    • aposiderophilin
    • apotransferrin
    • Beta-1 metal-binding globulin
    • ion free transferrin
    • PRO1557
    • PRO2086
    • Serotransferrin
    • Siderophilin
    • TF
    • TFQTL1
    • Transferrin
    • TRFE_HUMAN
    see all
  • 功能
    Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
  • 组织特异性
    Expressed by the liver and secreted in plasma.
  • 疾病相关
    Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
  • 序列相似性
    Belongs to the transferrin family.
    Contains 2 transferrin-like domains.
  • 细胞定位
    Secreted.
  • Information by UniProt

图片

  • SDS-PAGE: 4-12% Bis-Tris NuPAGE gel
    Lane 1: 5 µg Apotransferrin (reduced/heated)
    Lane 2: Molecular weight markers
    Lane 3: 5 µg Apotransferrin (non-reduced/no heat)
    Lane 4: 10 µg Apotransferrin (non-reduced/no heat)
    Lane 5: 20 µg Apotransferrin (non-reduced/no heat)

文献

ab91100 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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