Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.
Synthesized mainly in liver and to a minor degree in intestine. Secreted in plasma.
SDS-PAGE - Apolipoprotein CI protein (Human) (ab91139)
SDS-PAGE: 18% Tris Glycine gel
Lane 1. 10 µg Apolipoprotein CI (reduced/heated)
Lane 2. 20 µg Apolipoprotein CI (reduced/heated)
Lane 3. Molecular weight markers
Lane 4. 10 µg Apolipoprotein CI (non-reduced/no heat)
Lane 5. 20 µg Apolipoprotein CI (non-reduced/no heat)
has not yet been referenced specifically in any publications.