Natural人Apolipoprotein B (ab91112)

概述

描述

  • 性质
    Native
  • 来源
    Native
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab91112 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Lyophilised
  • 补充说明
    Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 50mM Sodium carbonate, 10mM Sodium Deoxycholate, pH 10.0

常规信息

  • 别名
    • Apo B-100
    • Apo B-48
    • APOB
    • ApoB 100
    • ApoB 48
    • APOB_HUMAN
    • Apolipoprotein B
    • Apolipoprotein B (including Ag(x) antigen)
    • Apolipoprotein B 100
    • Apolipoprotein B-48
    • Apolipoprotein B48
    • FLDB
    • LDLCQ4
    see all
  • 功能
    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • 疾病相关
    Hypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • 序列相似性
    Contains 1 vitellogenin domain.
  • 翻译后修饰
    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • 细胞定位
    Cytoplasm. Secreted.
  • Information by UniProt

图片

  • SDS-PAGE: 4-12% Bis-Tris-HCI NuPAGE gel
    Lane 1. 5 µg Apolipoprotein (reduced /heated)
    Lane 2. 10 µg Apolipoprotein (reduced/ heated)
    Lane 3. 20 µg Apolipoprotein (reduced/ heated)
    Lane 4. Molecular weight markers
    Lane 5. 5 µg Apolipoprotein (non-reduced/no heat)
    Lane 6. 10 µg Apolipoprotein (non-reduced/no heat)
    Lane 7. 20 µg Apolipoprotein (non-reduced/no heat)

文献

ab91112 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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