Natural牛Aprotinin protein (ab49828)

概述

  • 产品名称Natural牛Aprotinin protein
  • 蛋白长度Full length protein

描述

  • 性质Natural
  • 来源Native
  • 氨基酸序列
    • 种属Cow
    • 额外的序列信息Source of protein = Bovine lung

技术指标

Our Abpromise guarantee covers the use of ab49828 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Biological activity is 6 x 106 IU/mg.
  • 应用

    Inhibition Assay

  • 纯度> 95 % SDS-PAGE.
    Aprotinin is purified by proprietary chromatographic techniques. >98% by SDS-PAGE and HPLC analyses.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Add 1% BSA for extra stability. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Endotoxin level is <0.1 ng per µg of Aprotinin.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute with 1ml water for a concentration of 1mg/ml.

常规信息

  • 别名
    • Basic protease inhibitor
    • BPI
    • BPTI
    • Pancreatic trypsin inhibitor
    • PTI
    see all
  • 相关性Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges.
  • 细胞定位Secreted

Natural cow Aprotinin protein (ab49828)参考文献

ab49828 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"