The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
生物活性Biological activity is 6 x 106 IU/mg.
% SDS-PAGE. Aprotinin is purified by proprietary chromatographic techniques.
>98% by SDS-PAGE and HPLC analyses.
Concentration information loading...
Shipped at 4°C. Add 1% BSA for extra stability. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Endotoxin level is <0.1 ng per µg of Aprotinin.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
复溶Reconstitute with 1ml water for a concentration of 1mg/ml.
Basic protease inhibitor
Pancreatic trypsin inhibitor
相关性Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges.
Natural cow Aprotinin protein (ab49828)参考文献
has not yet been referenced specifically in any publications.