Natural Collagen V protein (ab7530)

概述

描述

  • 性质
    Native
  • 来源
    Native

相关产品

技术指标

Our Abpromise guarantee covers the use of ab7530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Collagen taken from bovine species.
  • 应用

    Western blot

    Immunoprecipitation

    ELISA

  • 形式
    Liquid
  • 补充说明

    This product reacts with anti-Collagen Type V. Reaction with anti-Collagen I, II, III, IV or VI is negligible (typically less than 1% cross reactivity was detected by ELISA).

    Collagen taken from bovine species.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 0.1M Sodium Acetate. pH 4.5

常规信息

  • 别名
    • AB collagen
    • Alpha 1 type V collagen
    • Alpha 2 type V collagen
    • CO5A1_HUMAN
    • COL5A1
    • Col5A2
    • COL5A2 protein
    • Col5A3
    • Collagen alpha 1(V) chain
    • Collagen alpha 2 (V) chain precursor
    • Collagen alpha 2(V) chain
    • Collagen alpha 3(V) chain
    • Collagen alpha-1(V) chain
    • Collagen fetal membrane A polypeptide
    • Collagen type V alpha 1
    • Collagen type V alpha 2
    • Collagen type V alpha 3
    • Collagen V alpha 2 polypeptide
    • CollagenV
    • MGC105115
    • OTTHUMP00000064637
    • Pro alpha 1 type V collagen
    • Pro alpha 3(V) collagen
    • Procollagen alpha 2(V)
    • Type V preprocollagen alpha 2 chain
    see all
  • 功能
    Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.
  • 疾病相关
    Ehlers-Danlos syndrome 1
    Ehlers-Danlos syndrome 2
  • 序列相似性
    Belongs to the fibrillar collagen family.
    Contains 1 fibrillar collagen NC1 domain.
    Contains 1 laminin G-like domain.
  • 结构域
    The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function.
  • 翻译后修饰
    Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
    Sulfated on 40% of tyrosines.
  • 细胞定位
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt

文献

ab7530 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your enquiry. This product has been prepared from Bovine Placenta and is chromatographically and immunologically pure. I enquired with our source for this protein and the originator said that it is sterile filtered and kept frozen. No rou...

Read More

The immunogen to make this antibody is derived from human and bovine placenta. The major isoform comprises two proalpha1 chains and one proalpha2 chain. The second isoform comprises proalpha1, proalpha2 and proalpha3 chains.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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