Natural B. pertussis Pertussis toxin protein (ab63830)

概述

  • 产品名称Natural B. pertussis Pertussis toxin protein
  • 蛋白长度Full length protein

描述

  • 性质Natural
  • 来源Native
  • 氨基酸序列
    • 种属Bordetella pertussis
    • 额外的序列信息Pertussis toxin protein consists of one molecule of each subunit 1 (26 kDa), subunit 2 (22 kDa), subunit 3 (22 kDa), subunit 5 (12 kDa) and two molecules of subunit 4 (12 kDa).

技术指标

Our Abpromise guarantee covers the use of ab63830 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Functional Studies

  • 形式Liquid
  • 补充说明


    ab63830 can be used for: 1. Studies on signal transduction by the trimeric GTP-binding proteins. 2. Therapeutic role in treating a number of diseases including hypertension, viral inhibition, and autoimumune inhibition.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.0268% PBS, 10% Glycerol, 0.8% Sodium chloride

常规信息

  • 别名
    • IAP S1
    • IAP S2
    • IAP S3
    • IAP S4
    • IAP S5
    • Islet activating protein S1
    • Islet activating protein S2
    • Islet activating protein S3
    • Islet activating protein S4
    • Islet activating protein S5
    • NAD dependent ADP ribosyltransferase
    • Pertussis toxin subunit 1
    • Pertussis toxin subunit 2
    • Pertussis toxin subunit 3
    • Pertussis toxin subunit 4
    • Pertussis toxin subunit 5
    • PTX S1
    • PTX S2
    • PTX S3
    • PTX S4
    • PTX S5
    • PtxA
    • PtxB
    • PtxC
    • PtxD
    • PtxE
    see all
  • 相关性Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by Bordetella pertussis. PT catalyzes the ADP-ribosylation of the alpha subunits of the heterotrimeric guanine nucleotide regulatory proteins Gi, Go, and Gt and prevents intracellular signal transduction by preventing the G proteins from interacting with G protein-coupled receptors on the cell membrane. PT consists of one molecule each of S1 (26 kDa), S2 (22 kDa), S3 (22 kDa), S5 (12 kDa) and two molecules of S4 (12 kDa).
  • 细胞定位Secreted

Natural B. pertussis Pertussis toxin protein 图像

  • ab63830 on SDS-PAGE.
  • Left Panel: Control CHO cell culture without Pertussis Toxin. Right Panel: CHO cells treated with Pertussis Toxin at 0.1 ng/ml in the culture medium for 17 hr at 37oC.

Natural B. pertussis Pertussis toxin protein (ab63830)参考文献

ab63830 has not yet been referenced specifically in any publications.

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Thank you for contacting us.

The protein can be shipped at 4C. However upon arrival it sould be stored at -80C.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information...

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Thank you for your patient. I can confirm the toxin was produced from phase 1 Bordetella pertussis Tohama strain. I hope this information is helpful. Please do not hesitate to contact us if you need further advice or information.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"