概述

  • 产品名称Natural AGE protein
  • 蛋白长度Full length protein

描述

  • 性质Natural
  • 来源Native

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技术指标

Our Abpromise guarantee covers the use of ab51995 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 纯度> 95 % SDS-PAGE.
    Purity > 98% 0.22 µm filter sterilized.
  • 形式Liquid
  • 补充说明May precipitate during extended storage. Sonicate to solubilize the precipitates. The AGE modified BSA was produced by reacting BSA with glycolaldehyde under sterile conditions followed by extensive dialysis and purification steps. Fluorescence of AGEs was confirmed by fluorescence spectrophotometry with Ex./Em. = 370/440 nm. Glycated BSA shows a 7000% increase in fluorescence in compared to control BSA.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: PBS

常规信息

  • 别名
    • Advanced glycation end products
    • AGEs
  • 相关性The non enzymatic reaction of reducing carbohydrates with lysine side chains and N terminal amino groups of macromolecules (amino acids, proteins, phospholipids and nucleic acids) is called the Maillard reaction or glycation. The latter products of this process, termed advanced glycation end products (AGEs), adversely affect the functional properties of proteins, lipids and DNA. In long lived tissue proteins, these chemical modifications accumulate with age and may contribute to the pathophysiology of ageing and long term complications of diabetes, atherosclerosis and renal failure.
  • 细胞定位Cell Membrane and Secreted

Natural AGE protein (ab51995)参考文献

ab51995 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"