概述

  • 产品名称Anti-NAT8L抗体
    参阅全部 NAT8L 一抗
  • 描述
    小鼠多克隆抗体to NAT8L
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    NAT8L recombinant fragment of the human protein (169 - 302 aa).

  • 阳性对照
    • NAT8L transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab69464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 36 kDa.

靶标

  • 功能Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.
  • 组织特异性Expressed in brain.
  • 序列相似性Belongs to the camello family.
    Contains 1 N-acetyltransferase domain.
  • 细胞定位Cytoplasm. Membrane. Microsome membrane. Mitochondrion membrane. Rough endoplasmic reticulum membrane. Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1110038O08Rik antibody
    • Camello-like protein 3 antibody
    • CML3 antibody
    • Hcml3 antibody
    • N acetyltransferase 8 like (GCN5 related, putative) antibody
    • N-acetylaspartate synthetase antibody
    • N-acetyltransferase 8-like protein antibody
    • NAA synthetase antibody
    • NAT8 like antibody
    • Nat8l antibody
    • NAT8L_HUMAN antibody
    • protein Shati antibody
    • Shati antibody
    see all

Anti-NAT8L antibody 图像

  • All lanes : Anti-NAT8L antibody (ab69464) at 1/500 dilution

    Lane 1 : FLJ37478 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 36 kDa
    Observed band size : 12 kDa (why is the actual band size different from the predicted?)

Anti-NAT8L antibody (ab69464)参考文献

This product has been referenced in:
  • Springer HM  et al. Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-?-induced mouse cells. J Immunol 191:1765-74 (2013). Read more (PubMed: 23842753) »

See 1 Publication for this product

Product Wall

Email to be sent to customer: Thank you for your enquiry to Sybille who is currently away. The whole sequence of the particular accession # NP_848652 was used for the antibody production. However, the sequence used in the overexpression WB is NP_84...

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Thank you for your enquiry. The immunogen does not include a tag sequence (for instance GST). There will be no cross-reaction with GST or other tag. I hope this information helps. Please do not hesitate to contact us if you need any more advice ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"