概述

  • 产品名称Anti-NARG1抗体
    参阅全部 NARG1 一抗
  • 描述
    兔多克隆抗体to NARG1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 816 and 866 of Human NARG1 (NP_476516.1).

  • 阳性对照
    • Human Breast Carcinoma, Colon Carcinoma, Prostate Carcinoma, Stomach Adenocarcinoma and Testicular Seminoma tissues.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituents: Tris buffered saline, 0.1% BSA
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111149 was affinity purified using an epitope specific to NARG1 immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

靶标

  • 功能The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter.
  • 组织特异性Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy.
  • 序列相似性Contains 8 TPR repeats.
  • 翻译后修饰Cleaved by caspases during apoptosis, resulting in a stable 35 kDa fragment.
  • 细胞定位Cytoplasm. Nucleus. Mainly cytoplasmic, nuclear in some cases. Present in the free cytosolic and cytoskeleton-bound polysomes, but not in the membrane-bound polysomes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5730450D16Rik antibody
    • 6330400I15 antibody
    • ASTBDN antibody
    • GA19 antibody
    • Gastric cancer antigen Ga19 antibody
    • MGC29428 antibody
    • mNAT1 antibody
    • N alpha acetyltransferase 15, NatA auxiliary subunit antibody
    • N terminal acetyltransferase antibody
    • N(alpha) acetyltransferase 15, NatA auxiliary subunit antibody
    • N-alpha-acetyltransferase 15 antibody
    • N-terminal acetyltransferase antibody
    • Naa15 antibody
    • NAA15_HUMAN antibody
    • NatA auxiliary subunit antibody
    • NATH antibody
    • NMDA receptor regulated 1 antibody
    • NMDA receptor regulated protein 1 antibody
    • NMDA receptor-regulated protein 1 antibody
    • Protein tubedown 1 antibody
    • Protein tubedown-1 antibody
    • Tbdn 1 antibody
    • Tbdn100 antibody
    • Transcriptional coactivator tubedown 100 antibody
    • tubedown-1 antibody
    see all

Anti-NARG1 antibody 图像

  • ab111149 at 1/250 dilution staining NARG1 in Human stomach carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.
    Detection: DAB staining.
  • ab111149 at 1/250 dilution staining NARG1 in Human testicular seminoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.
    Detection: DAB staining.

Anti-NARG1 antibody (ab111149)参考文献

ab111149 has not yet been referenced specifically in any publications.

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