The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa.
Use a concentration of 10 µg/ml.
功能May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.
序列相似性Belongs to the nucleosome assembly protein (NAP) family.
结构域The acidic domains are probably involved in the interaction with histones.
翻译后修饰Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human.
细胞定位Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.