概述

  • 产品名称Anti-Naked1抗体
    参阅全部 Naked1 一抗
  • 描述
    兔多克隆抗体to Naked1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 82-111 of Human Naked1 (NP_149110.1).

  • 阳性对照
    • Mouse heart tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab116107 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab116107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 52 kDa.

靶标

  • 相关性Naked1 (Nkd1) is a homologue of Drosophila Naked cuticle, a negative regulator of Wnt/Wingless signaling pathway. Naked proteins contain a putative calcium-binding EF-hand motif; however, Drosophila Naked binds to zinc instead of calcium. Naked inhibits the canonical Wnt/ß-catenin pathway by binding to Dishevelled proteins and directs Dishevelled activity towards the planar cell polarity pathway. Naked1 is a direct target of Wnt signaling and is overexpressed in some colon tumors due to constitutive activation of Wnt/ß-catenin pathway.
  • 细胞定位Cell membrane
  • 数据库链接
  • 别名
    • Dvl-binding protein antibody
    • Naked cuticle 1 antibody
    • naked cuticle 1 homolog antibody
    • Naked cuticle homolog 1 (Drosophila) antibody
    • Naked-1 antibody
    • NKD antibody
    • Nkd1 antibody
    • Protein naked cuticle homolog 1 antibody
    see all

Anti-Naked1 antibody 图像

  • Anti-Naked1 antibody (ab116107) at 1/100 dilution + Mouse heart tissue lysate at 35 µg

    Predicted band size : 52 kDa

Anti-Naked1 antibody (ab116107)参考文献

ab116107 has not yet been referenced specifically in any publications.

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