概述

  • 产品名称Anti-NADE抗体
    参阅全部 NADE 一抗
  • 描述
    兔多克隆抗体to NADE
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A 14 amino acid synthetic peptide from near the middle of NADE (Human).

性能

应用

Our Abpromise guarantee covers the use of ab21303 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 2 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 23 kDa (predicted molecular weight: 13 kDa).

靶标

  • 功能May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
  • 组织特异性Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
  • 序列相似性Belongs to the BEX family.
  • 结构域The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.
  • 翻译后修饰Ubiquitinated. Degraded by the proteasome.
  • 细胞定位Nucleus. Cytoplasm. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bex antibody
    • BEX3 antibody
    • BEX3_HUMAN antibody
    • Brain expressed X linked 3 (mouse) homolog antibody
    • brain expressed, X-linked 3 antibody
    • Brain-expressed X-linked gene 3 antibody
    • Brain-expressed X-linked protein 3 antibody
    • DXS6984E antibody
    • HGR74 antibody
    • Nerve growth factor receptor (TNFRSF16) associated protein 1 antibody
    • Nerve growth factor receptor associated protein 1 antibody
    • Nerve growth factor receptor-associated protein 1 antibody
    • NGFR-associated protein 1 antibody
    • NGFRAP1 antibody
    • Ovarian granulosa cell 13.0 kDa protein HGR74 antibody
    • ovarian granulosa cell protein (13kD) antibody
    • Ovarian granulosa cell protein antibody
    • p75NTR associated cell death executor antibody
    • p75NTR-associated cell death executor antibody
    • Protein BEX3 antibody
    see all

Anti-NADE antibody 图像

  • All lanes : Anti-NADE antibody (ab21303) at 1 µg/ml

    Lane 1 : human brain cell lysate with blocking peptide.
    Lane 2 : human brain cell lysate with Without blocking peptide.


    Predicted band size : 13 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)
  • ab21303 at 2µg/ml staining NADE in human brain tissue by IHC 

Anti-NADE antibody (ab21303)参考文献

This product has been referenced in:
  • Xiao L & Tsutsui T Three-dimensional epithelial and mesenchymal cell co-cultures form early tooth epithelium invagination-like structures: Expression patterns of relevant molecules. J Cell Biochem : (2012). Read more (PubMed: 22234822) »

See 1 Publication for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - whole cell (Small Cell Lung Cancer)
Loading amount 30 µg
Specification Small Cell Lung Cancer
Gel Running Conditions Reduced Denaturing (15% Gel)
Blocking step Milk as blocking agent for 18 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
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提交于 Nov 25 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"