Anti-Nab2抗体[cl.1C4] (ab11987)

概述

  • 产品名称Anti-Nab2抗体[cl.1C4]
    参阅全部 Nab2 一抗
  • 描述
    小鼠单克隆抗体[cl.1C4] to Nab2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein (Human).

  • 阳性对照
    • K-562 nuclear extract (TPA stimulated).

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab11987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 56-65 kDa (predicted molecular weight: 57 kDa).

靶标

  • 功能Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability.
  • 组织特异性Widely expressed at low levels. Highly expressed in melanoma cell lines.
  • 序列相似性Belongs to the NAB family.
  • 结构域The NAB conserved domain 1 (NCD1) interacts with EGR1 inhibitory domain and mediates multimerization.
    The NAB conserved domain 2 (NCD2) is necessary for transcriptional repression.
  • 细胞定位Nucleus. Isoform 2 is not localized to the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EGR 1 binding protein 2 antibody
    • EGR-1-binding protein 2 antibody
    • EGR1 binding protein 2 antibody
    • MADER antibody
    • Melanoma associated delayed early response protein antibody
    • Melanoma-associated delayed early response protein antibody
    • MGC75085 antibody
    • Nab 2 antibody
    • nab2 antibody
    • NAB2_HUMAN antibody
    • NGFI A binding protein 2 (EGR1 binding protein 2) antibody
    • NGFI A binding protein 2 antibody
    • NGFI-A-binding protein 2 antibody
    • Protein MADER antibody
    see all

Anti-Nab2 antibody [cl.1C4] 图像

  • Detection of Nab2 by Western blot analysis. Antibody experiment using Nab2 mouse monoclonal antibody demonstrates the presence of Nab2 transcription factor in nuclear extracts derived from K-562 cells (TPA) using a 1/1000 dilution

Anti-Nab2 antibody [cl.1C4] (ab11987)参考文献

ab11987 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Here is the information that I found about how to make this lysate: Cells were cultured in medium supplemented with 50 ng/ml TPA (phorbol, 12-myristate, 13 acetate) for two hours at 37°C immediately prior to harvesting....

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