概述

  • 产品名称Anti-Myt1抗体
    参阅全部 Myt1 一抗
  • 描述
    兔多克隆抗体to Myt1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    3 synthetic peptides (human) conjugated to KLH

  • 阳性对照
    • Induced culture of E.coli (one shot Top10 competent cells).

性能

应用

Our Abpromise guarantee covers the use of ab82844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: Use at an assay dependent dilution.
    Antibody specificity was verified by direct ELISA against the 3 immunogen peptides. A minimum titer of 1/50000 is determined for one of the three peptides.
    WB: 1/1000. Detects a band of approximately 136 kDa (predicted molecular weight: 136 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.
    • 组织特异性Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.
    • 序列相似性Contains 7 C2HC-type zinc fingers.
    • 结构域Contains 7 zinc fingers of the C2HC class arranged in two widely separated clusters. These two domains of DNA binding can function independently and recognize the same DNA sequence.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C20orf36 antibody
      • KIAA0835 antibody
      • KIAA1050 antibody
      • MTF1 antibody
      • Myelin transcription factor 1 antibody
      • Myelin transcription factor I antibody
      • MYT1 antibody
      • MYT1_HUMAN antibody
      • MyTI antibody
      • PLPB1 antibody
      • Proteolipid protein-binding protein antibody
      see all

    Anti-Myt1 antibody 图像

    • All lanes : Anti-Myt1 antibody (ab82844) at 1/1000 dilution

      Lane 1 : uninduced culture of E.coli (one shot Top10 competent cells)
      Lane 2 : induced culture of E.coli (one shot Top10 competent cells)

      Secondary
      anti-Rabbit IgG HRP at 1/1000 dilution

      Predicted band size : 136 kDa
      Observed band size : 136 kDa
      Additional bands at : 35 kDa,80 kDa. We are unsure as to the identity of these extra bands.

    Anti-Myt1 antibody (ab82844)参考文献

    This product has been referenced in:
    • Fernandez-Enright F  et al. Novel implications of Lingo-1 and its signaling partners in schizophrenia. Transl Psychiatry 4:e348 (2014). WB ; Human . Read more (PubMed: 24448210) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"