概述

  • 产品名称Anti-MYSM1抗体
    参阅全部 MYSM1 一抗
  • 描述
    兔多克隆抗体to MYSM1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    KLH conjugated synthetic peptide between amino acids 118-147 from the N-terminal region of Human MYSM1 (NP_001078956.1)

  • 阳性对照
    • MDA-MB231 cell lysate Mouse kidney tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab107542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 95 kDa.

靶标

  • 功能Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
  • 序列相似性Belongs to the peptidase M67A family. MYSM1 subfamily.
    Contains 1 MPN (JAB/Mov34) domain.
    Contains 1 SANT domain.
    Contains 1 SWIRM domain.
  • 结构域Binds double-stranded DNA via the SANT domain. The SWIRM domain does not bind double-stranded DNA.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2A-DUB antibody
    • 2ADUB antibody
    • Histone H2A deubiquitinase antibody
    • Histone H2A deubiquitinase MYSM1 antibody
    • KIAA1915 antibody
    • Myb like SWIRM and MPN domains 1 antibody
    • Myb like, SWIRM and MPN domain containing protein antibody
    • Myb like, SWIRM and MPN domains 1 antibody
    • Myb-like antibody
    • Myb-like, SWIRM and MPN domains 1 antibody
    • MYSM 1 antibody
    • mysm1 antibody
    • MYSM1 Myb-like, SWIRM and MPN domains 1 antibody
    • MYSM1_HUMAN antibody
    • RP4-592A1.1 antibody
    • SWIRM and MPN domain-containing protein 1 antibody
    see all

Anti-MYSM1 antibody 图像

  • Anti-MYSM1 antibody (ab107542) at 1/100 dilution + MDA-MB231 cell lysate at 35 µg

    Predicted band size : 95 kDa
  • Anti-MYSM1 antibody (ab107542) at 1/100 dilution + Mouse kidney tissue lysate at 35 µg

    Predicted band size : 95 kDa

Anti-MYSM1 antibody (ab107542)参考文献

ab107542 has not yet been referenced specifically in any publications.

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