概述

  • 产品名称Anti-Myozenin 2抗体
    参阅全部 Myozenin 2 一抗
  • 描述
    小鼠多克隆抗体to Myozenin 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human Myozenin 2 (AAH05195)

  • 阳性对照
    • Myozenin 2 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab89148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 30 kDa.

靶标

  • 功能Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
  • 组织特异性Expressed specifically in heart and skeletal muscle.
  • 疾病相关Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16) [MIM:613838]. CMH16 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
  • 序列相似性Belongs to the myozenin family.
  • 细胞定位Cytoplasm > myofibril > sarcomere > Z line. Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C4orf5 antibody
    • Calcineurin binding protein calsarcin 1 antibody
    • Calsarcin 1 antibody
    • Calsarcin-1 antibody
    • Calsarcin1 antibody
    • CMH16 antibody
    • CS 1 antibody
    • CS1 antibody
    • FATZ related protein 2 antibody
    • FATZ-related protein 2 antibody
    • Muscle specific protein antibody
    • MYOZ 2 antibody
    • MYOZ2 antibody
    • MYOZ2_HUMAN antibody
    • Myozenin-2 antibody
    • Myozenin2 antibody
    see all

Anti-Myozenin 2 antibody 图像

  • All lanes : Anti-Myozenin 2 antibody (ab89148) at 1/500 dilution

    Lane 1 : Myozenin 2 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 30 kDa
    Observed band size : 30 kDa

Anti-Myozenin 2 antibody (ab89148)参考文献

ab89148 has not yet been referenced specifically in any publications.

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