Anti-Myostatin Propeptide抗体[6E8] (ab37254)

概述

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: 0.1M Sodium chloride, 0.05M PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号6E8
  • 同种型IgG2b
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab37254 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 43 kDa.
IHC-P 1/100.

靶标

  • 功能Acts specifically as a negative regulator of skeletal muscle growth.
  • 疾病相关Defects in MSTN are the cause of muscle hypertrophy (MSLHP) [MIM:614160]. MSLHP is a condition characterized by increased muscle bulk and strength. Affected individuals are exceptionally strong.
  • 序列相似性Belongs to the TGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cmpt antibody
    • GDF-8 antibody
    • GDF8_HUMAN antibody
    • Growth/differentiation factor 8 antibody
    • MSLHP antibody
    • MSTN antibody
    • MSTN myostatin antibody
    • Myostatin antibody
    • Myostatin Propeptide antibody
    see all

Anti-Myostatin Propeptide antibody [6E8] 图像

  • IHC image of ab37254 staining in human pancreas formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab37254, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Myostatin Propeptide antibody [6E8] (ab37254)参考文献

ab37254 has not yet been referenced specifically in any publications.

Product Wall

I have performed a homology search of the first 270 amino acids of the human myostatin precursor with the cow protein and found a homology of 92%. As the antibody is monoclonal it will only recognise one epitope (unlike a polyclonal) and as this has ...

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Thank you for your enquiry regarding ab37254. This antibody was made in tissue culture. Where ascites has been used this will be detailed on the datasheet. Protein G purification is a simple method to select all immunoglobulins (non specifically...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"