概述

描述

  • 性质
    Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab4996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • 补充说明


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and myosin VIIa, catalog ab3481. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Deafness autosomal dominant 11
    • Deafness autosomal recessive 2
    • DFNA11
    • DFNB 2
    • DFNB2
    • Myo7a
    • Myosin 7a
    • Myosin VIIa
    • Myosin VIIA (Usher syndrome 1B (autosomal recessive, severe))
    • Myosin, unconventional, family VII, member A
    • MYOVIIA
    • MYU7A
    • NSRD 2
    • NSRD2
    • Unconventional myosin VIIa
    • Ush 1B
    • Ush1b
    • Usher syndrome 1B
    see all
  • 相关性
    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.
  • 细胞定位
    Cytoplasmic, cytoskeleton

文献

ab4996 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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