Anti-Myosin VIIa抗体(ab92996)

概述

  • 产品名称
    Anti-Myosin VIIa抗体
    参阅全部 Myosin VIIa 一抗
  • 描述
    兔多克隆抗体to Myosin VIIa
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Human, Pig
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1000 - 1100 of Mouse Myosin VIIa.

  • 阳性对照
    • This antibody gave a positive signal in mouse testis tissue lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab92996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 238 kDa (predicted molecular weight: 255 kDa).

靶标

  • 相关性
    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.
  • 细胞定位
    Cytoplasmic, cytoskeleton
  • 数据库链接
  • 别名
    • Deafness autosomal dominant 11 antibody
    • Deafness autosomal recessive 2 antibody
    • DFNA11 antibody
    • DFNB 2 antibody
    • DFNB2 antibody
    • Myo7a antibody
    • Myosin 7a antibody
    • Myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) antibody
    • Myosin VIIa antibody
    • Myosin, unconventional, family VII, member A antibody
    • MYOVIIA antibody
    • MYU7A antibody
    • NSRD 2 antibody
    • NSRD2 antibody
    • Unconventional myosin VIIa antibody
    • Ush 1B antibody
    • Ush1b antibody
    • Usher syndrome 1B antibody
    see all

Anti-Myosin VIIa antibody 图像

  • Anti-Myosin VIIa antibody (ab92996) at 1 µg/ml + Testis (Mouse) Tissue Lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 255 kDa
    Observed band size : 238 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 50 kDa,60 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 12 minutes

实验方案

Anti-Myosin VIIa antibody (ab92996)参考文献

ab92996 has not yet been referenced specifically in any publications.

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