Anti-Myosin Light Chain 2抗体(ab55460)

概述

  • 产品名称Anti-Myosin Light Chain 2抗体
    参阅全部 Myosin Light Chain 2 一抗
  • 描述
    小鼠单克隆抗体to Myosin Light Chain 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-167 of Human Myosin Light Chain 2

性能

应用

Our Abpromise guarantee covers the use of ab55460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 疾病相关Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic type 10 (CMH10) [MIM:608758]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
      Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic with mid-left ventricular chamber type 2 (MVC2) [MIM:608758]. MVC2 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.
    • 序列相似性Contains 3 EF-hand domains.
    • 翻译后修饰N-terminus is methylated by METTL11A/NTM1.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cardiac myosin light chain-2 antibody
      • Cardiac ventricular myosin light chain 2 antibody
      • CMH10 antibody
      • MLC 2v antibody
      • MLC-2 antibody
      • MLC-2v antibody
      • MLC2 antibody
      • MLRV_HUMAN antibody
      • MYL 2 antibody
      • MYL2 antibody
      • Myosin light chain 2 regulatory cardiac slow antibody
      • Myosin light polypeptide 2 regulatory cardiac slow antibody
      • Myosin regulatory light chain 2 antibody
      • Myosin regulatory light chain 2 ventricular/cardiac muscle isoform antibody
      • Regulatory light chain of myosin antibody
      • RLC of myosin antibody
      • Slow cardiac myosin regulatory light chain 2 antibody
      • ventricular/cardiac muscle isoform antibody
      see all

    Anti-Myosin Light Chain 2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab55460 Myosin Light Chain 2 antibody at 1ug/ml. Predicted band size of immunogen is 44 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-Myosin Light Chain 2 antibody (ab55460)参考文献

    ab55460 has not yet been referenced specifically in any publications.

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