Anti-MyoD1抗体[5.2F], prediluted (ab7272)

概述

  • 产品名称Anti-MyoD1抗体[5.2F], prediluted
    参阅全部 MyoD1 一抗
  • 描述
    小鼠单克隆抗体[5.2F] to MyoD1, prediluted
  • 特异性This antibody is specific to a 45 kD protein. This antibody does not react with myogenin, Myf5 or Myf6. MyoD1 stains the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue but is expressed strongly in the tumor cell nuclei of rhabdomyosarcomas.
  • 经测试应用适用于: IHC-Frmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    BALB/C mice were injected with a recombinant mouse MyoD1 protein.

  • 表位This antibody is specific to an epitope of amino acid 3-56 in the N-terminus of mouse MyoD1.
  • 阳性对照
    • Tonsil

性能

应用

Our Abpromise guarantee covers the use of ab7272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.

靶标

  • 功能Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.
  • 序列相似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 翻译后修饰Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function.
    Ubiquitinated on the N-terminus; which is required for proteasomal degradation.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bHLHc1 antibody
    • Class C basic helix-loop-helix protein 1 antibody
    • MYF 3 antibody
    • Myf-3 antibody
    • MYF3 antibody
    • Myoblast determination protein 1 antibody
    • Myod 1 antibody
    • MYOD antibody
    • MYOD1 antibody
    • MYOD1_HUMAN antibody
    • Myogenic differentiation 1 antibody
    • Myogenic factor 3 antibody
    • Myogenic factor MYF 3 antibody
    • Myogenin D1 antibody
    • PUM antibody
    see all

Anti-MyoD1 antibody [5.2F], prediluted (ab7272)参考文献

ab7272 has not yet been referenced specifically in any publications.

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