Anti-MYO5A抗体(ab110468)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to MYO5A
  • 特异性
    ab110468 detects endogenous levels of total MYO5A protein.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    A synthesized peptide derived from the C terminal region of Human MYO5A (UniProt ID: Q9Y4I1).

  • 阳性对照
    • Extracts from Hela cells.

性能

应用

Our Abpromise guarantee covers the use of ab110468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 215 kDa.

靶标

  • 功能
    Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.
  • 组织特异性
    Detected in melanocytes.
  • 疾病相关
    Griscelli syndrome 1
    Griscelli syndrome 3
    Elejalde syndrome
  • 序列相似性
    Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    Contains 1 dilute domain.
    Contains 6 IQ domains.
    Contains 1 myosin motor domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • non-muscle antibody
    • Dilute myosin heavy chain antibody
    • GS1 antibody
    • MYH12 antibody
    • MYO5 antibody
    • Myo5a antibody
    • MYO5A_HUMAN antibody
    • Myosin heavy chain 12 antibody
    • Myosin heavy polypeptide kinase antibody
    • Myosin V antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin-12 antibody
    • Myoxin antibody
    • MYR12 antibody
    • Unconventional myosin-Va antibody
    see all

Anti-MYO5A antibody 图像

  • All lanes : Anti-MYO5A antibody (ab110468) at 1/500 dilution

    Lane 1 : Extracts from Hela cells
    Lane 2 : Extracts from Hela cells, treated with the synthesized peptide

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 215 kDa

实验方案

Anti-MYO5A antibody (ab110468)参考文献

ab110468 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application
Western blot
Sample
Rat Tissue lysate - whole (Brain)
Gel Running Conditions
Reduced Denaturing (8%)
Loading amount
10 µg
Specification
Brain
Blocking step
BSA as blocking agent for 10 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Ansley Kunnath

Verified customer

提交于 Jul 21 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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