概述

  • 产品名称Anti-MYO5A抗体
    参阅全部 MYO5A 一抗
  • 描述
    山羊多克隆抗体to MYO5A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Chicken, Pig
  • 免疫原

    Synthetic peptide:

    C-ETKQLELDLN

    , corresponding to internal sequence amino acids 1063-1072 of Human MYO5A (NP_000250.3; NP_001135967.1).

  • 阳性对照
    • Jurkat cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab105024 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 200 kDa (predicted molecular weight: 215 kDa).Can be blocked with MYO5A peptide (ab201110).

靶标

  • 功能Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.
  • 组织特异性Detected in melanocytes.
  • 疾病相关Griscelli syndrome 1
    Griscelli syndrome 3
    Elejalde syndrome
  • 序列相似性Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    Contains 1 dilute domain.
    Contains 6 IQ domains.
    Contains 1 myosin motor domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • non-muscle antibody
    • Dilute myosin heavy chain antibody
    • GS1 antibody
    • MYH12 antibody
    • MYO5 antibody
    • Myo5a antibody
    • MYO5A_HUMAN antibody
    • Myosin heavy chain 12 antibody
    • Myosin heavy polypeptide kinase antibody
    • Myosin V antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin-12 antibody
    • Myoxin antibody
    • MYR12 antibody
    • Unconventional myosin-Va antibody
    see all

Anti-MYO5A antibody 图像

  • Anti-MYO5A antibody (ab105024) at 1 µg/ml + Jurkat cell lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 215 kDa

Anti-MYO5A antibody (ab105024)参考文献

ab105024 has not yet been referenced specifically in any publications.

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