概述

  • 产品名称
  • 描述
    山羊多克隆抗体to MYO5A
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Chicken, Pig
  • 免疫原

    Synthetic peptide:

    C-ETKQLELDLN

    , corresponding to internal sequence amino acids 1063-1072 of Human MYO5A (NP_000250.3; NP_001135967.1).

  • 阳性对照
    • Jurkat cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab105024 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 200 kDa (predicted molecular weight: 215 kDa).Can be blocked with MYO5A peptide (ab201110).

靶标

  • 功能
    Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.
  • 组织特异性
    Detected in melanocytes.
  • 疾病相关
    Griscelli syndrome 1
    Griscelli syndrome 3
    Elejalde syndrome
  • 序列相似性
    Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    Contains 1 dilute domain.
    Contains 6 IQ domains.
    Contains 1 myosin motor domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • non-muscle antibody
    • Dilute myosin heavy chain antibody
    • GS1 antibody
    • MYH12 antibody
    • MYO5 antibody
    • Myo5a antibody
    • MYO5A_HUMAN antibody
    • Myosin heavy chain 12 antibody
    • Myosin heavy polypeptide kinase antibody
    • Myosin V antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin-12 antibody
    • Myoxin antibody
    • MYR12 antibody
    • Unconventional myosin-Va antibody
    see all

图片

  • Anti-MYO5A antibody (ab105024) at 1 µg/ml + Jurkat cell lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 215 kDa

实验方案

文献

ab105024 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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