概述

  • 产品名称Anti-MYO1E抗体
    参阅全部 MYO1E 一抗
  • 描述
    兔多克隆抗体to MYO1E
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 1043-1092 of Human MYO1E (NP_004989).

  • 阳性对照
    • HepG2 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab98191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 127 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.
  • 组织特异性Expressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes.
  • 疾病相关Focal segmental glomerulosclerosis 6
  • 序列相似性Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    Contains 1 IQ domain.
    Contains 1 myosin motor domain.
    Contains 1 SH3 domain.
    Contains 1 TH1 (class I myosin tail homology) domain.
  • 细胞定位Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction. Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FSGS6 antibody
    • HuncM-IC antibody
    • MYO1C antibody
    • Myo1e antibody
    • MYO1E variant protein antibody
    • MYO1E_HUMAN antibody
    • Myosin heavy chain myr 3 antibody
    • Myosin IC, formerly antibody
    • Myosin IE antibody
    • Myosin-Ic antibody
    • Myr 3 antibody
    • Myr3 antibody
    • MYR5 antibody
    • Unconventional myosin 1E antibody
    • Unconventional myosin Ie antibody
    • Unconventional myosin-Ie antibody
    see all

Anti-MYO1E antibody 图像

  • Anti-MYO1E antibody (ab98191) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 127 kDa

Anti-MYO1E antibody (ab98191)参考文献

ab98191 has not yet been referenced specifically in any publications.

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