Anti-MYO18A抗体(ab81690)
Key features and details
- Rabbit polyclonal to MYO18A
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MYO18A抗体
参阅全部 MYO18A 一抗 -
描述
兔多克隆抗体to MYO18A -
宿主
Rabbit -
经测试应用
适用于: IPmore details -
种属反应性
与反应: Human
预测可用于: Rat, Gorilla, Orangutan -
免疫原
Synthetic peptide within Human MYO18A aa 2000 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. NP_510880.2
Database link: Q92614 -
阳性对照
- RIPA whole lysates from HeLa cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.09% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab81690 was affinity purified using an epitope specific to MYO18A immobilized on solid support. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab81690于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IP |
说明 |
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Is unsuitable for WB.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性
Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE) rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid associated lung collectin that mediates innate and adaptive immune responses in the lungs. -
细胞定位
Isoform 1: Endoplasmic reticulum Golgi intermediate compartment. Cytoplasm, cytoskeleton. Note: Colocalizes with actin. Isoform 2: Cytoplasm. Note: Lacks the PDZ domain. Diffusely localized in the cytoplasm. -
数据库链接
- Entrez Gene: 399687 Human
- Entrez Gene: 287905 Rat
- Omim: 610067 Human
- SwissProt: Q92614 Human
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别名
- MAJN antibody
- Molecule associated with JAK3 N terminus antibody
- Myosin 18A antibody
see all
图片
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Detection of human MYO18A by Western Blot of Immunoprecipitates.
Samples: RIPA whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.
ab81690 used for IP at 3 µg/mg lysate (lane 2).
MYO18A was also immunoprecipitated by rabbit anti MYO18A (ab81689), which recognizes an upstream epitope (lane 1).
Lane 3 represents the control IgG.
For blotting immunoprecipitates, ab81689 was used at 1 µg/ml.
Detection: by Chemiluminescence with an exposure time of 1 second.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab81690 尚未被引用在任何文献中。