Anti-Myeloperoxidase抗体[7,17] (FITC) (ab91237)

概述

  • 产品名称Anti-Myeloperoxidase抗体[7,17] (FITC)
    参阅全部 Myeloperoxidase 一抗
  • 描述
    小鼠单克隆抗体[7,17] to Myeloperoxidase (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性ab91237 reacts with virtually all cells of the myeloid lineage (from myekloblast to neutrophils and monocytes). ab91237 does not react with Human lymphocytes, thrombocytes and erythrocytes. 96% of all AML's are found positive; 100% of all ALL's are found negative.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human myeloperoxidase from CML cells

  • 阳性对照
    • Normal Human peripheral blood

性能

应用

Our Abpromise guarantee covers the use of ab91237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 20 µl for 106 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
    • 疾病相关Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
    • 序列相似性Belongs to the peroxidase family. XPO subfamily.
    • 细胞定位Lysosome.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 84 kDa myeloperoxidase antibody
      • 89 kDa myeloperoxidase antibody
      • EC 1.11.1.7 antibody
      • EC1.11.2.2 antibody
      • fj80f04 antibody
      • MPO antibody
      • mpx antibody
      • myeloid-specific peroxidase antibody
      • Myeloperoxidase antibody
      • Myeloperoxidase heavy chain antibody
      • Myeloperoxidase light chain antibody
      • PERM_HUMAN antibody
      • wu:fj80f04 antibody
      see all

    Anti-Myeloperoxidase antibody [7,17] (FITC) 图像

    • ab91237, at 20 µl / 106 cells, staining Myeloperoxidase in normal Human peripheral blood, by Flow Cytometry.

    Anti-Myeloperoxidase antibody [7,17] (FITC) (ab91237)参考文献

    ab91237 has not yet been referenced specifically in any publications.

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